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Associate Professor   |   Ph.D.

Joo-Eun Kim

국민대학교 응용화학부 바이오의약전공 산업약학연구실

Industrial pharmaceutical Lab, Biopharmaceutical Chemistry Major, School of Applied Chemistry,

Kookmin University

​학력

  • 고려대학교 생명공학 학사(2003)

  • 고려대학교 생명공학 석사(2005)

  • ​아주대학교 약학대학 박사(2017)

경력사항

  • 2022.09 ~ 현재 : 국민대학교 조교수 -산업약학연구실(신약/개량신약/제네릭)

  • 2019.03 ~ 현재 : (사)대한약학회 분과위원 - (사)대한약학회 산업약학분과

  • 2019.01 ~ 현재 : 국가신약개발사업 기획위원회 기획위원 - 국가신약연구개발 사업화지원 3분과

  • 2018.03 ~ 현재 : Journal of pharmaceutical investigation 편집간사 - Associate editor

  • 2018.03 ~ 현재 : (사)한국약제학회 편집위원 - (사)한국약제학회 편집분과

  • 2018.02 ~ 현재 : 식품의약품안전처 평가위원 - 의약품 규격과/의약품 품질과

  • 2016.09 ~ 현재 : 한국제약기술교육원 강사 - QbD교육, 생산화연구 강사

  • 2018.02 ~ 2022.08 : 대구가톨릭대학교 제약공학과 교수 - 산업약학연구실(신약/개량신약/제네릭)

  • 2016.12 ~ 2018.02 : (주)유한양행 수석연구원/Project Leader - 신약개발/QbD/개량신약/OTC/제네릭

  • 2013.12 ~ 2016.02 : (주)유한양행 책임연구원/TFT팀장 - 신약개발/QbD/개량신약/OTC/제네릭

  • 2010.01 ~ 2013.12 : (주)유한양행 선임연구원 - 신약개발/개량신약/OTC/제네릭

  • 2008.01 ~ 2009.12 : (주)유한양행 주임연구원 - 신약개발/제품개발팀

  • 2005.08 ~ 2007.12 : (주)유한양행 연구원 - 신약개발/나노입자연구

  • 2005.06 ~ 2005.08 : (주)삼성엔지니어링 연구원 - R&D전략기획팀

  • 2002.07 ~ 2002.12 : 서울대학교 연구원 - 의과학연구소(연건동)

논문/저서

  • Paclitaxel-loaded hyaluronan solid nanoemulsions for enhanced treatment efficacy in ovarian cancer, International journal of nanomedicine, 2017

  • High paclitaxel-loaded and tumor cell-targeting hyaluronan-coated nanoemulsions, Colloids and surfaces b-biointerfaces, 2017

  • Improved Antitumor Efficacy of Hyaluronic Acid-Complexed Paclitaxel Nanoemulsions in Treating Non-Small Cell Lung Cancer, Biomolecules therapeutics, 2017

  • Development of stabilized tenofovir disoproxil tablet: degradation profile, stabilization, and bioequivalence in beagle dogs, Drug development and industrial pharmacy, 2018

  • Quality-by-design approach for the development of telmisartan potassium tablets, Drug development and industrial pharmacy, 2018

  • Preparation of Silica Microparticles as Volatile Material Carrier and Their Sustained-Release Property, Journal of nanoscience and nanotechnology, 2019

  • Transformer-ethosomes with palmitoyl pentapeptide for improved transdermal delivery, Journal of drug delivery science and technology, 2019

  • 설계기반품질고도화(QbD)의약품 개발을 위한 오픈소스 기반 실험설계 R 프로그램의 활용, 약학회지, 2019

  • Nanotechnology in the arena of cancer immunotherapy, Archives of pharmacal research, 2020

  • Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs, Pharmaceutics, 2021

  • Quality by Design Applied Development of Immediate-Release Rabeprazole Sodium Dry-Coated Tablet, Pharmaceutics, 2021

  • Development of an Analysis System to Support the Determination of Whether to Separate the Evaluation of Majors and Non-Major, 한국정보기술학회 논문지, 2021

  • Development and Validation of a Reversed-phase High Performance Liquid Chromatography Method for the Simultaneous Estimation of Rosuvastatin Calcium and Telmisartan in Fixed-Dose Complex Dual-Layer Tablets in Six Dosage Forms, Indian Journal of Pharmaceutical Sciences, 2021

  • Analysis of Perception and Status Survey on the Introduction of QbD System by Pharmaceutical Companies in Korea, 약학회지, 2021

  • Hyaluronan Self-Agglomerating Nanoparticles For NonSmall Cell Lung Cancer Targeting, Cancer nanotechnology, 2021

  • QbD Consideration for Developing a Double Layered Tablet into a Single-Layered Tablet with Telmisartan and Amlodipine, Pharmaceutics, 2022

  • Studies on Preformulation and Formulation of JIN-001Liquisolid Tablet with Enhanced Solubility, Pharmaceuticals, 2022

  • In Vitro-In vivo Correlation of Tianeptine SoldiumSustained-Release Dual-Layer Tablets, Molecules, 2022

  • Development of Nafamostat Mesylate Immediate-Release Tablet by Drug Repositioning Using Quality-by-Design Approach, Pharmaceuticals, 2022

  • Quality by Design (QbD) application for the pharmaceutical development, J.Pharm.Inv., 2022

  • Design of experiment (DoE)-based formulation design of bepotastine sustained-release tablet and in vitro-in vivo pharmacokinetic correlation, J.Pharm.Inv., 2023

  • Development of Clinically Optimized Sitagliptin and Dapagliflozin Complex Tablets: Pre-Formulation, Formulation, and Human Bioequivalence Studies, Pharmaceuticals, 2023

  • The Development and Validation of Simultaneous Quantitative Analysis Reversed-phase High-performance Liquid Chromatography for Sitagliptin Phosphate Monohydrate and Dapagliflozin Propanediol Monohydrate Fixed-dose Combination Dual-layered Tablet, Current Pharmaceutical Analysis, 2023

  • Application of continuous manufacturing for solid oral dosage forms, J.Pharm.Inv., 2023

  • Perfluorocarbon-based artificial oxygen carriers for red blood cell substitutes: considerations and direction of technology J.Pharm.Inv., 2024

  • ​국내외 특허출원 및 등록 19편

의약품 기술 적용 사례

  • 펙수프라잔 동결건조주사제 QbD 적용

  • 탄산수소나트륨-라베프라졸 복합유핵정 허가

  • 시타글립틴-다파글로플로진 이층정 허가

  • 인공지능 의약품설계 플랫폼 출시

  • 피타바스타틴-페노피브레이트 이층정 완료

  • 탄산수소나트륨-일라프라졸 유핵정 완료

  • 타다라필 츄어블정/지르텍 츄어블정 완료

  • 티아넵틴 서방정 개발(위체류정) 완료

  • ​텔미/암로 복합이층정(듀오웰제네릭정)개발

산학협력 가능 분야

  • 신약 Preformulation/Formulation 연구

  • 개량신약/제네릭 등 의약품개발 및 인허가

  • IND 자료 및 NDA 자료작성(CTD 작성포함)

  • 특수제형(주사제, 동결건조, 점이, 점안제)

  • ​인공지능 제형설계/제조공정

  • ​지능형 연속공정 적용 연구

Contact

Tel   02-910-4763

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